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Discover how cryo-EM structure determination canaccelerate drug development

Microscopic black and white image of 2D class averaging with cryo-EM | Nanoparticle characterization | Structural Biology | Nano Imaging

2D Class Averaging

Cryo-EM or negative stain imaging can be used for the 2D classification of individual particles from TEM micrographs to classify particles, and visualize particle flexibility.

Scientific rendering of 3D Protein Structure Reconstruction with Cryo-EM | Nano Imaging

3D Reconstruction of Structures

Use cryo-EM & advanced data processing to generate high resolution 3D maps & models of challenging molecules and membrane proteins, over 76% below 3.5Å.

3D reconstruction of Epitope Mapping of antibody-antigen complex by cryo-EM | Structural Biology | NanoImaging Services

Epitope Mapping

Cryo-EM & negative stain TEM can be used to assess the binding interactions of antibody-antigen complexes. Explore how TEM can elucidate Fab binding across a range of resolutions.

cryo-em microscopic image of single particle analysis of protein | structural biology | nano imaging services

Cryo-EM Feasibility Assessment

Quickly visualize your protein or drug target in under two weeks to better assess the next steps in your single particle or structure based drug design workflow.

Gene-to-Structure Protein Consultancy

Partner with NIS to enhance your gene-to-structure workflow and maximize your success in obtaining high-resolution protein structures with cryo-EM.

Scientific rendering of Single Particle Analysis (SPA) with cryo-EM | Nano Imaging

Single Particle Cryo-EM

Get accurate and reliable high resolution protein structure determination with cryo-EM single particle analysis techniques.

Scientific rendering of cryo-EM structure determination of hERG services

Structure Determination of the anti target hERG

Accurate & reliable off target hERG structure determination with high resolution cryo-EM data collection.

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